Plakophilin 1 Protein (PKP1) (AA 1-728) (His tag)

Catalog No. ABIN7556786

This Recombinant Plakophilin 1 protein is expressed in HEK-293 Cells.

Quick Overview for Plakophilin 1 Protein (PKP1) (AA 1-728) (His tag) (ABIN7556786)

Target: Plakophilin 1 (PKP1)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-728

Purification tag / Conjugate: This Plakophilin 1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Pkp1 Protein expressed in mammalian cells.

Sequence: MNHSPLKTAL AYECFQDQDN STLALPSDQK MKTGTSGRQR VQEQVMMTVK RQKSKSSQSS TLSHSNRGSM YDGLADNYNN YGTTSRSSYF SKFQAGNGSW GYPIYNGTLK REPDNRRFSS YSQMENWSRH YPRGSCATPG AGSDICFMQK IKASRSEPDL YCDPRGTLRK GTLGSKGHKT TQNRCSFYST CSGQKAVKKC PVRPPSCTSK QDPVYVPPIS CNKDLSFGHS RASSKICSED IECSGLTIPK AVQYLCSQDE KYQAIGAYYI QHTCFQDESA KQQVYQLGGI CKLVDLLRSP NQNVQQAAAG ALRNLVFRST PNKLETRRQN GIREAVSLLR RSGSTEIQKQ LTGLLWNLSS TDELKEELVA DALPVLTDRV IIPFSGWCDG NSNMSREVVD PEVFFNATGC LRNLSSADAG RQTMRNYSGL IDSLMAYVQN CVAASRCDDK SVENCMCILH NLSYRLDAEV PTRYRQLEYN TRNAYTEKSS TGCFSNRGDK MMNNNYDCPL PEEETNPKGS SWLYHSDAIR TYLNLMGKSK KDATLEACAG ALQNLTASKG LMSNGMSQLI GIKEKGLPQI ARLLQSGNSD VVRSGASLLS NMSRHPVLHR VMGNQVFPEV TRLLTSHTGN TSNSEDILSS ACYTVRNLMT SQPQMAKQYF SNSMLNNVFN LCRNTASSPK AAEAARLLLS DMWASKELQS VLRQQGFDRN MMGNIAGANN LRNFTSRF Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Plakophilin 1 (PKP1)

Alternative Name: Pkp1

Background: Plakophilin-1,FUNCTION: Seems to play a role in junctional plaques (By similarity). May facilitate the formation of intermediate filaments (By similarity). {ECO:0000250|UniProtKB:Q13835}.

Molecular Weight: 80.9 kDa

UniProt: P97350

AlphaFold: P97350