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Plakophilin 1 Protein (PKP1) (Myc-DYKDDDDK Tag)

PKP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729111
  • Target See all Plakophilin 1 (PKP1) Proteins
    Plakophilin 1 (PKP1)
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    Human
    Source
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Plakophilin 1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Plakophilin 1 / PKP1 (transcript variant 1a) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PKP1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Plakophilin 1 (PKP1)
    Alternative Name
    Plakophilin 1,pkp1 (PKP1 Products)
    Synonyms
    PKP1 Protein, fb30d08 Protein, wu:fb30d08 Protein, AI528551 Protein, B6P Protein, plakophilin 1 Protein, plakophilin 1b Protein, PKP1 Protein, pkp1b Protein, Pkp1 Protein
    Background
    This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    80.3 kDa
    NCBI Accession
    NP_001005337
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