INSC Protein (AA 1-579) (His tag)

Catalog No. ABIN7557033

Recombinant INSC protein expressed in HEK-293 Cells.

Quick Overview for INSC Protein (AA 1-579) (His tag) (ABIN7557033)

Target: INSC (Inscuteable Homolog (INSC))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-579

Purification tag / Conjugate: This INSC protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Insc Protein expressed in mammalian cells.

Sequence: MRRPPGDGDS TGEGPGNWGL WGAQESRRLC CVGPDRCGQA LLQIGINMMA LPGGRHLDSV PLQEQRLHFM QVDSVQRWME DLKLMTECEC MCVLQAKPIS LEEDTQGDLI LAGGPGPGDP LQLLLKRGWV ISTELRRIGQ KLAQDRWARV HSMSVRLTCH ARSMVSEYST ISRTASQEMG QAEKLLMEKC SELSAVTERC LQVENEHVLK SMKACVSETL SLLGEHFGQL LELALTREVQ ALVRKIDTSD NIYITESTTG NLFGLTQEGA PLCRIIAKEG GVVALFKVCR QDSFRCLYPQ ALRTLASICC VEEGVHQLEK VDGILCLADI LTDESHSEAT RAEAAAVVAQ VTSPHLSFTQ HLTSFLENME EIVTALIKLC QEASSGEVFL LASAALANIT FFDKMACEML LQLNAIRVLL EACGDKQRVD TPYTRDQIVT ILANMSVLEQ CGSDIIQENG VQLIMGMLSE KPRSGTPAEV AACERVQQKA AVTLARLCRD PDVAQEAVRL SCMSRLIELC RSPSERNSSD AVLVACLAAL RRLAGVCPEG LQDSDFQQLV QPRLVDSFLL CSNMEESFV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: INSC (Inscuteable Homolog (INSC))

Alternative Name: Insc

Background: Protein inscuteable homolog (Minsc),FUNCTION: May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis (PubMed:16301171, PubMed:21816348). May regulate cell proliferation and differentiation in the developing nervous system (PubMed:16301171). May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium (PubMed:16094321). {ECO:0000269|PubMed:16094321, ECO:0000269|PubMed:16301171, ECO:0000269|PubMed:21816348}.

Molecular Weight: 63.6 kDa

UniProt: Q3HNM7

AlphaFold: Q3HNM7