BRD9 Protein (AA 1-596) (His tag)

Catalog No. ABIN7557258

Product Details

Target: BRD9 (Bromodomain Containing 9 (BRD9))

Protein Type: Recombinant

Protein Characteristics: AA 1-596

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This BRD9 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Brd9 Protein expressed in mammalian cells.

Sequence: MGKKHKKHKA EWRSSYEDYT DTPLEKPLKL VLKVGGSEVT ELSGSGHDSS YYDDRSDHER ERHREKKKKK KKKSEKEKHL DEEERRKRKE EKKRKREKEH CDSEGEADAF DPGKKVEVEP PPDRPVRACR TQPAENESTP IQRLLEHFLR QLQRKDPHGF FAFPVTDAIA PGYSMIIKHP MDFGTMKDKI VANEYKSVTE FKADFKLMCD NAMTYNRPDT VYYKLAKKIL HAGFKMMSKA ALLGSEDPAA EEPVPEVVPV QVETTKKSKK PSREVISCMF EPEGNACSLT DSTAEEHVLA LVEHAADEAR DRINRFLPGG KMGYLKKLGD GSLLYSVVNA PEPDADEEET HPVDLSSLSS KLLPGFTTLG FKDERRNKVT FLSSASTALS MQNNSVFGDL KSDEMELLYS AYGDETGVQC ALSLQEFVKD AGSYSKKMVD DLLDQITGGD HSRMIFQLKQ RRSIPMRPAD EMKVGDPLGE SGGPVLDFMS MKQYPDVSLD VSMLSSLGKV KKELDHEDSH LNLDETARLL QDLHEAQAER GGSRPSSNLS SLSTASEREH PPPGSPSRLS VGEQPDVAHD PYEFLQSPEP AAPAKN Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: BRD9 (Bromodomain Containing 9 (BRD9))

Alternative Name: Brd9 (BRD9 Products)

Background: Bromodomain-containing protein 9,FUNCTION: Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR). {ECO:0000250|UniProtKB:Q9H8M2}.

Molecular Weight: 66.8 kDa

UniProt: Q3UQU0

AlphaFold: Q3UQU0