BRD9 Protein (AA 130-259) (His tag,DYKDDDDK Tag)
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- Target See all BRD9 Proteins
- BRD9 (Bromodomain Containing 9 (BRD9))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 130-259
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BRD9 protein is labelled with His tag,DYKDDDDK Tag.
- Application
- Binding Studies (Bind), Screening Assay (ScA)
- Characteristics
- The peptide corresponding to amino acids 130 - 259 that contains the bromodomain sequences of BRD9 (accession number NM_023924.4) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.9 kDa.
- Top Product
- Discover our top product BRD9 Protein
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- Application Notes
- Recombinant BRD9 (130-259) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
- Restrictions
- For Research Use only
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- Handling Advice
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -80 °C
- Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- Target
- BRD9 (Bromodomain Containing 9 (BRD9))
- Alternative Name
- BRD9 (BRD9 Products)
- Synonyms
- LAVS3040 Protein, PRO9856 Protein, AL022779 Protein, zgc:55797 Protein, BRD9 Protein, bromodomain containing 9 Protein, bromodomain containing 9 L homeolog Protein, BRD9 Protein, Brd9 Protein, brd9 Protein, brd9.L Protein
- Background
- Bromodomain-containing protein 9 (BRD9) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6) that function in the regulation of transcriptional activation and chromatin remodeling. There are five isoforms of BRD9 that are produced by alternative splicing.
- Molecular Weight
- 20.9 kDa
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