RGL3 Protein (AA 1-709) (His tag)

Catalog No. ABIN7557314

This Recombinant RGL3 protein is expressed in HEK-293 Cells.

Quick Overview for RGL3 Protein (AA 1-709) (His tag) (ABIN7557314)

Target: RGL3 (Ral Guanine Nucleotide Dissociation Stimulator-Like 3 (RGL3))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-709

Purification tag / Conjugate: This RGL3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Rgl3 Protein expressed in mammalian cells.

Sequence: MERTAGKELA LAPLQDWGEE TEDGAVYSVS LRRQRSQRST PERSGEGQTP IPATDTFLHY RTSKVRALRA ARLERLVHEL VSGDREQDPG FVPAFLATHR AFVPTARVLG FLLPPPPPPP PPPAGVDSKR TEGQDLNFSK NLRAVVSVLG SWLRNHPQDF RDPPDHQNLG NVRIFLGWAA PGGAEAREAE KLLEDFLKEA KGEQTEEEKR LAWSGPPRIA QTPGSEFAED CVEEEGPSSE GPELLDFSVD DVAEQLTLMD VELFLRVRSC ECLGSMWSQR DRPGAAGISP TVRATVAQFN TVTGCVLGSV LAAPGLAASQ RAQRIEKWIR IAQRCRELRN FSSLRAILSA LQSNPIYRLK RSWGAVSREP LSVFRKLSQI FSDEDNHLSS RAILSQEETT EDDDCPSGSL PSKLPPGPVP YLGTFLTDLV MLDTALPDTL KGNLINFEKR RKEWEILARI QQLQQRCQRY SLSPRPPILA ALRAQRQLSE EQSYRVSRVI EPPAASCPSS PRIRRRISLT KRLSAKLSRE KNSSPGGSPG DPSSPTSSVS PGSPPSSPRN REPPPPGSPP ASPGPQSPST KLSLTMDPPG PWPVTLTPSS SRVPLLGQQT SEARVIRVSI NNNHGNLYRS ILLTCQDKAP SVVQRALEKH NVPQPWARDY QLFQVLPGDR ELLIPDGANV FYAMSPAAPG DFLLRRKEGT GHTLSASPT Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RGL3 (Ral Guanine Nucleotide Dissociation Stimulator-Like 3 (RGL3))

Alternative Name: Rgl3

Background: Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) (RalGDS-related effector protein of M-Ras) (Ras pathway modulator) (RPM),FUNCTION: Guanine nucleotide exchange factor (GEF) for Ral-A. Potential effector of GTPase HRas and Ras-related protein M-Ras. Negatively regulates Elk-1-dependent gene induction downstream of HRas and MEKK1. {ECO:0000269|PubMed:10869344, ECO:0000269|PubMed:11313946}.

Molecular Weight: 77.9 kDa

UniProt: Q3UYI5

AlphaFold: Q3UYI5