CEP44 Protein (AA 1-386) (His tag)

Catalog No. ABIN7557460

This Recombinant CEP44 protein is produced in HEK-293 Cells.

Quick Overview for CEP44 Protein (AA 1-386) (His tag) (ABIN7557460)

Target: CEP44 (Centrosomal Protein 44kDa (CEP44))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-386

Purification tag / Conjugate: This CEP44 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Cep44 Protein expressed in mammalian cells.

Sequence: MATGDLKRSL RKLEQVLRSL NYPNEVDYVG LIKGDTAASL PIISYSLTSY SPYVAELLME SSIELIAKND VRFTDTVYKL LRDQFDYKPI LTKKQFIQSG FAEWKIEIVC DILNCVMKKH KELIGLDKNS SCQRKKNVSE KPEPCSNSEK RPAEAVGIDI TGRFMTSGKK KAVVIRHLYT DEKVGVPEGT VTLADISQGC SESAEQSSDI RIPEAQDPEV KAELQDICDH PEITALQIAL AECQEKLKQL TWIEKRLERL EAATHGKVMV DEKAWNNLLS RVTLLETEML LSKKSESVER NVASQDCESI SDVDFVPYDK NYSVGGAAGN YRSSGCSAVS SETAPGSSIV NYCVLREFSE ETTIQKMERM KKMFEETAEL LKCSSR Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CEP44 (Centrosomal Protein 44kDa (CEP44))

Alternative Name: Cep44

Background: Centrosomal protein of 44 kDa (Cep44),FUNCTION: Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall. Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome. {ECO:0000250|UniProtKB:Q9C0F1}.

Molecular Weight: 43.3 kDa

UniProt: Q5HZK1

AlphaFold: Q5HZK1