MNS1 Protein (AA 1-491) (His tag)

Catalog No. ABIN7557745

This Recombinant MNS1 protein is produced in HEK-293 Cells.

Quick Overview for MNS1 Protein (AA 1-491) (His tag) (ABIN7557745)

Target: MNS1 (Meiosis-Specific Nuclear Structural 1 (MNS1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-491

Purification tag / Conjugate: This MNS1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Mns1 Protein expressed in mammalian cells.

Sequence: MATKKRALSF SEKHQKLVDE KFRKSLNIQV MNKLERQAKN QVVQNENDEK VERQRFLRVL QNEQFELDME EAIQKAEANK MLRDRQLEQE ERLANELARL KHESLKDKKM RQQVRENSIE LRELEQKLKA AYMNKERAAQ IVEKDAMKYE QMKRDAEIER IMMEEHDRLL KEESAKQERR NKERAQYYLD LEKQLEDQER RKQEAYEQLL KEKLMIDEIV RKIYEEDQVE RQQKLEKKNA IQKYIEEFQR AQDFWRQKKR EEMEEENRKI IEFANIQEQR EGERMARVHE IEEKRVQRQN LLMKQLEETL RQRDDLEQVR QELYQEEQAE IIKLKVKEEA ELRLRRQREM KQDFEDQMAL KELILQAAKE EEETFKKAML AKFAEDDRIE LMNAQKQRMK QLEHKRAVEK LIEERRSQFL ADKQRELEEL QLQQRRQGCI NEIIEEERLR LLKEHAAKLL GYLPKGVFKR EDDVDMLGEE FRKAYQKRDG V Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: MNS1 (Meiosis-Specific Nuclear Structural 1 (MNS1))

Alternative Name: Mns1

Background: Meiosis-specific nuclear structural protein 1,FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity). May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly (PubMed:22396656). May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules (By similarity). {ECO:0000250|UniProtKB:Q8NEH6, ECO:0000269|PubMed:22396656, ECO:0000269|PubMed:8032679}.

Molecular Weight: 60.2 kDa

UniProt: Q61884

AlphaFold: Q61884