Anoctamin 5 Protein (ANO5) (AA 1-904) (His tag)

Catalog No. ABIN7558160

This Recombinant Anoctamin 5 protein is expressed in HEK-293 Cells.

Quick Overview for Anoctamin 5 Protein (ANO5) (AA 1-904) (His tag) (ABIN7558160)

Target: Anoctamin 5 (ANO5)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-904

Purification tag / Conjugate: This Anoctamin 5 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Ano5 Protein expressed in mammalian cells.

Sequence: MVEQEGLTAK EIDYAFQQNE NLGSKETSFL IPEDLQSPPE KRFNLFLRRR LMFQRSEHSK DSVFFRDGIR QIDFVLSYVE DLKKDGELKA ERRREFEQNL RKTGLDLETE DKLNSEDGKT YFVKIHAPWE VLVTYAEVLG IKMPIKLSDI PRPKYPPLSY MLGAVKLPSS VKYPTPEYFT AQFSRHRQEL FLIEDEATFF PSSTRNRIVY YILSRCPFGV EEGKKKIGIE RLLNSNTYLS AYPLHDGQYW KPSKTTRPNE RYNLCKNWAR FSYFYKEQPF HLIRNYFGEK IGIYFVFLGY YTEMLLFAAL VGLACFIYGL LSMENNRTST EICDPDIGGQ MIMCPLCDEV CDYWRLNTTC LHSKFSHLFD NESTVFFALF MGIWVTLFLE FWKQRQARLE YEWDLVDFEE EQQQLQLRPE FEAMCKHKKM NPVTKEMEPH MPLCHRIPWY FVSGTTVTFG MALLLSSMVS ILIYRLSVFA TFASFMESEA TLQSVKSFFT PQLATALSGS CLNCIVILIL NFFYEKISAW ITKMEIPRTH QEYESSLTLK MFLFQFVNYY SSCFYVAFFK GKFVGYPGSY TYMFNIWRSE ECGPAGCLIE LTTQLTIIMI GKQIFGNIHE AFQPLIFNWW RRRRARTHSE KLYSRWEQDH DLQVYGHRGL FYEYLETVIQ FGFATLFVAS FPLAPLFALM NNIMGIRVDA WKLTTQYRRP VAAKAHSIGV WQDILFGMAI VSVATNAFIV SFTSDIIPRL VYFYAYSTNS TEPLSGYVNN SLSVFLIADF PNHTVPMEKK DFVTCRYRDY RYPPDHEDKY SHNMQFWHVL AAKMTFIIVM EHVVFLFKFL LAWLIPDVPK DVVEKIKREK LMTIKIIHDF ELNKLKENLD VEYGNIMKNV LVDEDNSLKA KTTV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Anoctamin 5 (ANO5)

Alternative Name: Ano5

Background: Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein homolog) (Transmembrane protein 16E),FUNCTION: Plays a role in plasma membrane repair in a process involving annexins (PubMed:33496727). Does not exhibit calcium-activated chloride channel (CaCC) activity. {ECO:0000250|UniProtKB:Q75V66, ECO:0000269|PubMed:33496727}.

Molecular Weight: 106.2 kDa

UniProt: Q75UR0

AlphaFold: Q75UR0