ANKRD13A Protein (AA 1-588) (His tag)

Catalog No. ABIN7558338

Recombinant ANKRD13A protein expressed in HEK-293 Cells.

Quick Overview for ANKRD13A Protein (AA 1-588) (His tag) (ABIN7558338)

Target: ANKRD13A (Ankyrin Repeat Domain 13A (ANKRD13A))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-588

Purification tag / Conjugate: This ANKRD13A protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Ankrd13a Protein expressed in mammalian cells.

Sequence: MSSARDTSSR FPLHLLVWNN DYEQLEKELR DQNAEALDPR GRTLLHLAVS LGHLESARVL LRHKADVTKE NGQGWTVLHE AVSTGDPEMV YTVLQHRDYH NTSMALEGVP ELLHKILEAP DFYVQMKWEF TSWVPLVSRI CPNDVCRIWK SGAKLRVDIT LLGFENMSWI RGRRSFIFKG GDNWAELMEV NHDDRVVTTE HFDLSQEMER LTLDLMKPKS REVERRLTSP VINTSLDTKN VAFERTKSGF WGWRTDKAEV VNGYEAKVYS VNNVSVITRI RTEHLTEEEK KRYKEDRNPL ESLLGTVEHQ FGAQGDLATE CATVNNPTAI TPDEYFDEDF DLKDRDIGRP KELTIRTQKF KATLWMCEEF PLSLVEQVIP IIDLMARTSA HFARLRDFIK LDFPPGFPVK IEIPLFHVLN ARITFGNVNG CSTADESQGV EGTPAEAVSE ATNFEVDQSV FEIPESYHIQ DNGRNVHLQD EDYEIMQFAI QQSLLESSRS QDLSGPASNG GVSHTHSYEA QYERAIQESL LTNMEGRCPG GLSESSRFDS DLQLAMELSA KELAERELRL QEEEAELQQV LQLSLTEK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ANKRD13A (Ankyrin Repeat Domain 13A (ANKRD13A))

Alternative Name: Ankrd13a

Background: Ankyrin repeat domain-containing protein 13A,FUNCTION: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). {ECO:0000250}.

Molecular Weight: 67.2 kDa

UniProt: Q80UP5

AlphaFold: Q80UP5