Deltex Homolog 3 Protein (AA 1-347) (His tag)
custom-made
DTX3
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all Deltex Homolog 3 (DTX3) Proteins
- Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-347
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Deltex Homolog 3 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Dtx3 Protein expressed in mammalian cells.
- Sequence
- MSFVLSRMAA CGGSCKNKVT VSKPVWDFLS KETPARLARL REEHRVSILI DGETSDIYVL QLSPQGPPPA PPNGLYLARK ALKGLLKEAE KELKKAQRQG ELMGCLALGG GGEHPELHRP GPPPLRAAPL LPPGARGLPP PPPPLPPPLP PRLREDAEEQ ETTCPICLGE IQNAKTLEKC RHSFCEGCIT RALQVKKACP MCGRFYGQLV GNQPQNGRML VSKDATLLLP SYEKYGTIVI QYVFPPGVQG AEHPNPGVRY PGTTRVAYLP DCPEGNKVLT LFRKAFDQRL TFTIGTSMTT GRPNVITWND IHHKTSCTGG PQLFGYPDPT YLTRVQEELR AKGITDD Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Deltex Homolog 3 (Drosophila) (DTX3) (AA 1-347) protein (His tag)
custom-made DTX3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))
- Alternative Name
- Dtx3 (DTX3 Products)
- Background
- Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (mDTX3) (RING-type E3 ubiquitin transferase DTX3),FUNCTION: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. {ECO:0000250}.
- Molecular Weight
- 38.0 kDa
- UniProt
- Q80V91
- AlphaFold
- Q80V91
- Pathways
- Notch Signaling
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