DLEC1 Protein (AA 1-635) (His tag)

Catalog No. ABIN7558734

Recombinant DLEC1 protein expressed in HEK-293 Cells.

Quick Overview for DLEC1 Protein (AA 1-635) (His tag) (ABIN7558734)

Target: DLEC1 (Deleted in Lung and Esophageal Cancer 1 (DLEC1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-635

Purification tag / Conjugate: This DLEC1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Dlec1 Protein expressed in mammalian cells.

Sequence: MDSESKEEQQ CTASSAVMSS LETQFLSVPH QLESASLSWS IRKSLHSSTV LMDDCHFGFP TRSLRAGFHA LPPLPEPQTL RLRPASLRTQ EISHLLARVF RNLYTAQVIG DDLSDSLIKA RGSEDARHEE FLDQLQQARA IYKQRLDEAA MLERHIMQAR ARDIAETEHT TKQSRLQVVE TPVKLPPVKT AFRWCLDSKL MRKHHLISTE DYYTDPVPFC PAPKDKSTLG CSKLTFSCEQ RFLRKSELDR EAEEHCRQLT ECDDFEYTVD SLGSISKAKE RTTDSVKKTS RPKNKKWMEH LQVPQRALDR RLLASMENRN HFLKNPRFFP PNTPHGGKSL IVPLSKPERR ASLNAEPEWS CTDAPVFLAK PSVGFFTDYE IGPVYEMVIA LQNTTSTSRF LRVLPPSSPY FALGLGMFPG KGGIVAPGMT CQYIVQFIPD CLGDFDDFIL VETQSPHTLV IPLQARRPPP VLTLSPVLDC GHCLIGGVKI TKFICKNVGF SVGKFCIMPQ KSWPPPSFRA VATTGFVEQP PFGVMPSVFE LAPGYAILLE VLFLPTGLGQ AEETFIIVCD NCQIKEVVVV GTGQLVALDL IHISGGKNEP DPGELKDLTA QYFIRFEPEN VQSTPKKQLI IRNAT Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: DLEC1 (Deleted in Lung and Esophageal Cancer 1 (DLEC1))

Alternative Name: Dlec1

Background: Deleted in lung and esophageal cancer protein 1 homolog,FUNCTION: Essential for spermatogenesis and male fertility (PubMed:33144677). May play an important role in sperm head and tail formation (PubMed:33144677). May act as a tumor suppressor by inhibiting cell proliferation (By similarity). {ECO:0000250|UniProtKB:Q9Y238, ECO:0000269|PubMed:33144677}.

Molecular Weight: 71.2 kDa

UniProt: Q8BLA1

AlphaFold: Q8BLA1