ARHGEF6 Protein (AA 1-771) (His tag)

Catalog No. ABIN7559572

This Recombinant ARHGEF6 protein is produced in HEK-293 Cells.

Quick Overview for ARHGEF6 Protein (AA 1-771) (His tag) (ABIN7559572)

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-771

Purification tag / Conjugate: This ARHGEF6 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Arhgef6 Protein expressed in mammalian cells.

Sequence: MNPEERLVTW LISLGVLESP KKTVCDPEEF LKSSLKNGVV LCKLINRLLP GSVEKYCLEP QTEADCIDNI NDFLKGCATL QVEVFEPDDL YSGANFSKVL NTLLAVNKAT EDQLSERPCG RSSSLSAATS SQTNPQVAVP STAPEQHSEE KAEMTENGSH QLIVKARFNF KQTNEDELSV CKGDIIYVTR VEEGGWWEGT LNGRTGWFPS NYVREIKPSE RPLSPKAIKG FDTAPLTKNY YTVVLQNILD TEKEYAKELQ SLLVTYLRPL QSNNNLSTVE FTCLLGNFEE VCTFQQTLCQ ALEECSKFPE NQHKVGGCLL NLMPHFKSMY LAYCANHPSA VNVLTQHSDD LERFMENQGA SSPGILILTT SLSKPFMRLE KYVTLLQELE RHMEDTHPDH QDILKAIIAF KTLMGQCQDL RKRKQLELQI LSEPIQAWEG DDIKTLGNVI FMSQVVMQHG ACEEKEERYF LLFSSVLIML SASPRMSGFM YQGKIPIAGM VVNRLDEIEG SDCMFEITGS TVERIVVHCN NNQDFQEWME QLNRLTKGPT SCGSLSKTSS SSCSTHSSFS STGQPRGPLE PPQIIKPWSL SCLRPAPPLR PSAALGYKER MSYILKESSK SPKTMKKFLH KRKTERKASE EEYVIRKSTA ALEEDAQILK VIEAYCTSAS FQQGTRKDSV PQVLLPEEEK LIIEETRSNG QTIIEEKSLV DTVYALKDEV KELKQENKKM KQCLEEELKS RKDLEKLVRK LLKQTDECIR SESSSKTSIL Q Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Alternative Name: Arhgef6

Background: Rho guanine nucleotide exchange factor 6 (Alpha-PIX) (Rac/Cdc42 guanine nucleotide exchange factor 6),FUNCTION: Acts as a RAC1 guanine nucleotide exchange factor (GEF). {ECO:0000250}.

Molecular Weight: 87.1 kDa

UniProt: Q8K4I3

AlphaFold: Q8K4I3

Pathways: Neurotrophin Signaling Pathway