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ELAC1 Protein (ELAC1) (AA 1-362) (His tag)

This Recombinant ELAC1 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7559900
starts at
$12,595.45
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 41 to 67 Business Days

Quick Overview for ELAC1 Protein (ELAC1) (AA 1-362) (His tag) (ABIN7559900)

Target

See all ELAC1 Proteins
ELAC1

Protein Type

Recombinant

Origin

  • 5
  • 1
  • 1
Mouse

Source

  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade

custom-made
  • Protein Characteristics

    AA 1-362

    Purification tag / Conjugate

    This ELAC1 protein is labelled with His tag.

    Purpose

    Predefined custom protein recombinant Elac1 Protein expressed in mammalian cells.

    Sequence

    MSMDVTFLGT GAAYPSPTRG ASAVVLRCEG ECWLFDCGEG TQTQLMKSQL KAGRITKIFI THLHGDHFFG LPGLLCTISL QSGSVVARQP IEIYGPVGLR DFIWRTMELS HTELVFPYVV HELVPTADQC PVEELREFAH MDETDSSPKG QGRTILLDAE ENSYCLVDDE QFVVKAFRLF HRIPSFGFSV VEKKRAGKLN AQKLRDLGVP PGPAYGKLKN GISVVLDNGV TISPQDVLKK PMVGRKVCIL GDCSGVVGDG GVKLCFEADL LIHEATLDDS QMDKAREHGH STPQMAAAFA KLCRAKRLVL THFSQRYKPT ALAREGEADG IAELRKQAEA VLELQEVTLA EDFMVIGIPI KK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

    Specificity

    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

    Characteristics

    Key Benefits:
    • Predefined custom protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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  • Application Notes

    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    The buffer composition is at the discretion of the manufacturer.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C.

    Expiry Date

    12 months
  • Target

    ELAC1

    Alternative Name

    Elac1

    Background

    Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (ElaC homolog protein 1) (Ribonuclease Z 1) (RNase Z 1) (tRNA 3 endonuclease 1) (tRNase Z 1),FUNCTION: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1. {ECO:0000250|UniProtKB:Q9H777}.

    Molecular Weight

    39.7 kDa

    UniProt

    Q8VEB6

    AlphaFold

    Q8VEB6
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