METTL18 Protein (AA 1-362) (His tag)
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- Target See all METTL18 Proteins
- METTL18 (Methyltransferase Like 18 (METTL18))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-362
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This METTL18 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant Mettl18 Protein expressed in mammalian cells.
- Sequence
- MAFQFNFSIE EDLENKLTSL DDGTCVLESQ KGKQDKRQST ERPGLPRDHS WKCSSLGNAA SSEDTGSPPP IADRSDDPEA CKHQPSWKPA KEHVMPKDVN HVLENTVLEM LPGPQHANTA VVKTVSLKEK FPGENIVSKS FSSHSDLIPG VYEGGLKIWE CTFDLLTYFT KAKVKFAGQK VLDLGCGSGL LGITASKGGA REVHFQDYNG LVIDEVTLPN VVANVPLQDD SNGKNEPDGK RQRKSEVGRE ICKCRLFSGE WAEFCKLVLR EKLFVKYDLI LTSETIYNPD YYSTLHETFL RLLSRSGRVL LASKAHYFGV GGGVHLFQKF VEEKGVFETR TLEVIDEGLK RFLMEMTFKH PS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product METTL18 Protein
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Methyltransferase Like 18 (METTL18) (AA 1-372) protein (His tag)
custom-made METTL18 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Methyltransferase Like 18 (METTL18) (AA 1-115) protein (His tag)METTL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Methyltransferase Like 18 (METTL18) protein (Myc-DYKDDDDK Tag)METTL18 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- METTL18 (Methyltransferase Like 18 (METTL18))
- Alternative Name
- Mettl18 (METTL18 Products)
- Background
- Histidine protein methyltransferase 1 homolog (EC 2.1.1.85) (Methyltransferase-like protein 18),FUNCTION: Protein-L-histidine N-tele-methyltransferase that specifically monomethylates RPL3, thereby regulating translation elongation. Histidine methylation of RPL3 regulates translation elongation by slowing ribosome traversal on tyrosine codons: slower elongation provides enough time for proper folding of synthesized proteins and prevents cellular aggregation of tyrosine-rich proteins. {ECO:0000250|UniProtKB:O95568}.
- Molecular Weight
- 40.4 kDa
- UniProt
- Q9CZ09
- AlphaFold
- Q9CZ09
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