F162A Protein (AA 1-155) (His tag)
Quick Overview for F162A Protein (AA 1-155) (His tag) (ABIN7561056)
Target
See all F162A (FAM162A) ProteinsProtein Type
Origin
Source
Purity
Grade
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Protein Characteristics
- AA 1-155
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Purification tag / Conjugate
- This F162A protein is labelled with His tag.
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Purpose
- Predefined custom protein recombinant Fam162a Protein expressed in mammalian cells.
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Sequence
- MWSLGGLRLA AGHCLRLYER NASSSLRFTR NTDLKRINGF CTKPQESPKT PTQSYRHGVP LHKPTDFEKK ILLWSGRFKK EEEIPETISF EMLDAAKNKL RVKVSYLMIA LTVAGCIYMV IEGKKAAKRH ESLTSLNLER KARLREEAAM KAKTD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The buffer composition is at the discretion of the manufacturer.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C.
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Expiry Date
- 12 months
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- F162A (FAM162A) (Family with Sequence Similarity 162, Member A (FAM162A))
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Alternative Name
- Fam162a
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Background
- Protein FAM162A (E2-induced gene 5 protein homolog) (Growth and transformation-dependent protein) (HGTD-P),FUNCTION: Proposed to be involved in regulation of apoptosis, the exact mechanism may differ between cell types/tissues (PubMed:15082785). May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition (PubMed:15082785). May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus, however, the involvement of caspases has been reported conflictingly (PubMed:17316997). {ECO:0000269|PubMed:15082785, ECO:0000269|PubMed:17316997}.
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Molecular Weight
- 17.7 kDa
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UniProt
- Q9D6U8
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AlphaFold
- Q9D6U8
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Pathways
- Positive Regulation of Endopeptidase Activity, SARS-CoV-2 Protein Interactome
Target
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