GNB1L Protein (AA 1-326) (His tag)

Catalog No. ABIN7561389

Recombinant GNB1L protein expressed in HEK-293 Cells.

Quick Overview for GNB1L Protein (AA 1-326) (His tag) (ABIN7561389)

Target: GNB1L (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1-Like (GNB1L))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-326

Purification tag / Conjugate: This GNB1L protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Gnb1l Protein expressed in mammalian cells.

Sequence: MAALFPPPPG PRFVLRGTQS AVNTLHFCPP SQAAGNPLLF SGSQNGLVHI WSLQTRRIVT TLNGHGGQGV IWLKTLPQGH QLLSQGRDLR LCLWDLEEGR NTIMDSVQLD SVGFCRGSIL VRGQQCWMLA VPGKGSDEVQ ILEMPSKTSV CTLKPEADAR PGMPMCLGLW QTNSSLRPLL LAGYEDGSVT LWDISERKVC SQITCHEEPV MGLDFDSQKA KGISGSAGKV LAVWSLDDQQ SLQVKKTHEL TNPGIAEVTI RPDHKILATA GWDHRIRVFH WRTMKPLAVL AFHSAPVYCV AFAADGLLAA GSKDQRISIW SLYPCP Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: GNB1L (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1-Like (GNB1L))

Alternative Name: Gnb1l

Background: Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF),FUNCTION: Acts as a critical regulator of DNA damage response (DDR) signaling via specifically regulating phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. {ECO:0000250|UniProtKB:Q9BYB4}.

Molecular Weight: 35.7 kDa

UniProt: Q9EQ15

AlphaFold: Q9EQ15