RCL1 Protein (AA 1-373) (His tag)

Catalog No. ABIN7561605

Recombinant RCL1 protein expressed in HEK-293 Cells.

Quick Overview for RCL1 Protein (AA 1-373) (His tag) (ABIN7561605)

Target: RCL1 (RNA Terminal Phosphate Cyclase-Like 1 (RCL1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-373

Purification tag / Conjugate: This RCL1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Rcl1 Protein expressed in mammalian cells.

Sequence: MATQAHSLSY AGCNFLRQRL VLSTLSGRPV KIRRIRARDD NPGLRDFEAS FIRLLDKITN GSRIEINQTG TTLYYQPGLL YGGSVEHDCS VLRGIGYYLE ALLCLAPFMK HPLKIVLRGV TNDQVDPSVD VLKATALPLL KQFGIDGESF ELKILRRGMP PGGGGEVLFS CPVRKVLKPV QLTDPGKIKR IRGMAYSVRV SPQMANRIVD SARSILNKFI PDIYIYTDHM KGVSSGKSPG FGLSLVAETT NGTFLSAELA SNPQGQGAAV LPEDLGRNCA KLLLEEIYRG GCVDSTNQSL VLLLMTLGQQ DVSKVLLGPL SPYTIEFLRH LKSFFQVMFK VETKPCGEEL KGGDKVLMTC VGIGFSNLSK TLK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RCL1 (RNA Terminal Phosphate Cyclase-Like 1 (RCL1))

Alternative Name: Rcl1

Background: RNA 3'-terminal phosphate cyclase-like protein,FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity). Does not have cyclase activity (By similarity). {ECO:0000250|UniProtKB:Q08096, ECO:0000250|UniProtKB:Q9Y2P8}.

Molecular Weight: 40.8 kDa

UniProt: Q9JJT0

AlphaFold: Q9JJT0