Gm1564 (AA 1-965) protein (His tag)

Catalog No. ABIN7561905

Recombinant Gm1564 protein expressed in HEK-293 Cells.

Quick Overview for Gm1564 (AA 1-965) protein (His tag) (ABIN7561905)

Target: Gm1564

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-965

Purification tag / Conjugate: His tag

Purpose: Predefined custom protein recombinant Meioc Protein expressed in mammalian cells.

Sequence: MEVSGGDTCR PRHPQGLREG PEPKVAAAAA AFRGSANRCW NLSVDTSNRL SDVFNSMMLT GSAPFYDCYK SQNEDNVDLR QTCTPLSSST EYASSIDSSL FYAPWSTYGD DIKQPPSSQI SVKNRIQTER NDYGSETDLY GLVSNILEEQ DKSQPYFAEG TCSSNLKSVW PMNTSRFVDH HDLLTEPKRP VDTSISQQAF YSGESVSAVE KQYLHNSSLT PQQKIDELYH GYTGLDLEEQ WLYLSRSDHS NCYNSQANDT VKATFQEYPF VKNCFTPQTG LSDIMKESGI DTYAYGREKI CTKGLETPLQ HKRAEIFLSQ FNRYNENADY CRYPEYAHPN KAKLNKCSNF SVQDGKKLAN GTPETPTVEA DAYTKLFQVK PANQKKMEET IPDQQNFAFP KTTPHLTEKQ FAKEAAFTAD FGLKSEYGLK PHTACPTNND FANVSEKQQF AKPDPLNSEY FKSVNLFSNS ATSSGGISLN RPTWMNVQTK NNLPIPYRNQ GNLMKLNSHL SAASKGSNHS SDFPQLSSTN LTSNSNLFQK YCQENPSAFS SFDFSYNGAE RIQSVNHMEG LTKTGEDNLF ESVTEKKIKQ PNGFCDSYSA SQYGIIENVN KHNFQAKPQS GHYDPEDIPK HFDGLPQNTY QDLLESQGHF NSHRQGSGDN NINSRVNRTQ ASCFSNNYMM GDLRHNQGFQ QLGSNGFPLR STHPFGHSVV PLLDSYDLFS YDDLSHLYPY FNDMMYGDNS FSGFVPTFGF QRPIKTRSGP ASELHIRLEE CYEQWRALEK ERKKTELALA KNYPGKKVSS TNNTPIPRLT SNPSRVDRLI VDELREQARV VTLLGKMERL RSSPLHANIS TALDRHLESI HIVQSRRKDE IVNASNRQRQ GVPRCQDDRD VFALATAIKE MCVATRKART TLWCALQMTL PKTASTAGQA DMEKAFQDLV NCEEKVHESI NSSNPMNQRG ETSKH Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Gm1564

Alternative Name: Meioc

Background: Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein),FUNCTION: Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle (PubMed:28380054). {ECO:0000269|PubMed:26742488, ECO:0000269|PubMed:28380054}.

Molecular Weight: 108.8 kDa

UniProt: A2AG06

AlphaFold: A2AG06