Neuregulin 3 Protein (NRG3) (AA 1-713) (His tag)
custom-made
NRG3
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
-
- Target See all Neuregulin 3 (NRG3) Proteins
- Neuregulin 3 (NRG3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-713
- Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Neuregulin 3 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Nrg3 Protein expressed in mammalian cells.
- Sequence
- MSEGAAGASP PGAASAAAAS AEEGTAAAAA AAAAGGGPDG GGEGAAEPPR ELRCSDCIVW NRQQTWLCVV PLFIGFIGLG LSLMLLKWIV VGSVKEYVPT DLVDSKGMGQ DPFFLSKPSS FPKAMETTTT TTSTTSPATP SAGGAASSRT PNRISTRLTT ITRAPTRFPG HRVPIRASPR STTARNTAAP PTVLSTTAPF FSSSTPGSRP PMPGAPSTQA MPSWPTAAYA TSSYLHDSTP SWTLSPFQDA AAASSSSPSS TSSTTTTPET STSPKFHTTT YSTERSEHFK PCRDKDLAYC LNDGECFVIE TLTGSHKHCR CKEGYQGVRC DQFLPKTDSI LSDPTDHLGI EFMESEDVYQ RQVLSISCII FGIVIVGMFC AAFYFKSKKQ AKQIQEHLKE SQNGKNYSLK ASSTKSESLM KSHVHLQNYS KADRHPVTAL EKIMESSFSA PQSFPEVTSP DRGSQPIKHH SPGQRSGMLH RNTFRRAPPS PRSRLGGIVG PAYQQLEESR IPDQDTIPCQ GIEVRKTISH LPIQLWCVER PLDLKYVSNG LRTQQNASIN MQLPSRETNP YFNSLDQKDL VGYLSPRANS VPIIPSMGLE ETCMQMPGIS DVKSIKWCKN SYSADIVNAS MPVSDCLLEE QQEVKILLET VQEQIRILTD ARRSEDFELA SMETEDSASE NTAFLPLSPT AKSEREAQFV LRNEIQRDSV LTK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
-
Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
-
Want other Options for this Protein ?
!Discover Our Catalog and Custom Protein Service Options!Your project requires further customization? Contact us and discover our custom protein solutions
-
Neuregulin 3 (NRG3) (AA 1-720) protein (His tag)
custom-made NRG3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
-
- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
-
- Target
- Neuregulin 3 (NRG3)
- Alternative Name
- Nrg3 (NRG3 Products)
- Background
- Pro-neuregulin-3, membrane-bound isoform (Pro-NRG3) [Cleaved into: Neuregulin-3 (NRG-3)],FUNCTION: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. {ECO:0000269|PubMed:9275162}.
- Molecular Weight
- 77.4 kDa
- UniProt
- O35181
- AlphaFold
- O35181
- Pathways
- RTK Signaling
-
You are here:
