KLC2 Protein (AA 1-599) (His tag)

Catalog No. ABIN7562604

Product Details

Target: KLC2 (Kinesin Light Chain 2 (KLC2))

Protein Type: Recombinant

Protein Characteristics: AA 1-599

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This KLC2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Klc2 Protein expressed in mammalian cells.

Sequence: MATMVLPREE KLSQDEIVLG TKAVIQGLET LRGEHRALLA PLASHEAGEA EPGSQERCLL LRRSLEAIEL GLGEAQVILA LSSHLGAVES EKQKLRAQVR RLVQENQWLR EELAGTQQKL QRSEQAVAQL EEEKQHLLFM SQIRKLDEML PQEEKGDVPK DSLDDLFPNE DEQSPAPSPG GGDVAAQHGG YEIPARLRTL HNLVIQYASQ GRYEVAVPLC KQALEDLEKT SGHDHPDVAT MLNILALVYR DQNKYKDAAH LLNDALAIRE KTLGKDHPAV AATLNNLAVL YGKRGKYKEA EPLCKRALEI REKVLGKFHP DVAKQLSNLA LLCQNQGKAE EVEYYYRRAL EIYATRLGPD DPNVAKTKNN LASCYLKQGK YQDAETLYKE ILTRAHEKEF GSVNGENKPI WMHAEEREES KDKRRDRRPM EYGSWYKACK VDSPTVNTTL RTLGALYRPE GKLEAAHTLE DCASRSRKQG LDPASQTKVV ELLKDGSGRG HRRGSRDVAG PQSESDLEES GPAAEWSGDG SGSLRRSGSF GKLRDALRRS SEMLVRKLQG GGPQEPNSRM KRASSLNFLN KSVEEPVQPG GRVFLTAAL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: KLC2 (Kinesin Light Chain 2 (KLC2))

Alternative Name: Klc2 (KLC2 Products)

Background: Kinesin light chain 2 (KLC 2),FUNCTION: Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends. {ECO:0000250|UniProtKB:Q9H0B6}.

Molecular Weight: 66.7 kDa

UniProt: O88448

AlphaFold: O88448