MXD1 Protein (AA 1-227) (His tag)

Catalog No. ABIN7563364

This Recombinant MXD1 protein is produced in HEK-293 Cells.

Quick Overview for MXD1 Protein (AA 1-227) (His tag) (ABIN7563364)

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-227

Purification tag / Conjugate: This MXD1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Mxd1 Protein expressed in mammalian cells.

Sequence: MATAVGMNIQ LLLEAADYLE RREREAEHGY ASMLPYSKDR DAFKRRNKPK KNSTSSRSTH NEMEKNRRAH LRLCLEKLKG LVPLGPESSR HTTLSLLTKA KLHIKKLEDC DRKAVHQIDQ LQREQRHLKR RLEKLGAERT RMDSVGSVVS SERSDSDREE LDVDVDVDVD VDVEGTDYLN GDLGWSSSVS DSDERGSMQS LGSDEGYSSA TVKRAKLQDG HKAGLGL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Alternative Name: Mxd1

Background: Max dimerization protein 1 (Max dimerizer 1) (Protein MAD),FUNCTION: Component of a transcriptional repressor complex together with MAX (By similarity). In complex with MAX binds to the core DNA sequence 5'-CAC[GA]TG-3' (By similarity). Antagonizes MYC transcriptional activity by competing with MYC for MAX binding (By similarity). Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding (By similarity). {ECO:0000250|UniProtKB:Q05195}.

Molecular Weight: 25.6 kDa

UniProt: P50538

AlphaFold: P50538