SOS2 Protein (AA 1-1333) (His tag)

Catalog No. ABIN7563582

Recombinant SOS2 protein expressed in HEK-293 Cells.

Quick Overview for SOS2 Protein (AA 1-1333) (His tag) (ABIN7563582)

Target: SOS2 (Son of Sevenless Homolog 2 (SOS2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1333

Purification tag / Conjugate: This SOS2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Sos2 Protein expressed in mammalian cells.

Sequence: MQQAPQPYEF FSEENSPKWR GLLVPALRKV QEQVHPTLSA NEESLYYIEE LIFQLLNKLC MAQPRTVQDV EERVQKTFPH PIDKWAIADA QSAIEKRKRR NPLLLPVDKI HPSLKEVLGY KVDYHVSLYI VAVLEYISAD ILKLAGNYVF NIRHYEISQQ DIKVSMCADK VLMDMFDQDD DIGLVSLCED EPCSSGELNY YDLVRTEIAE ERQYLRELNM IIKVFREAFL LDRKLFKPSE IEKIFSNISD IHELTVKLLG LIEDTVEMTD ESSPHPLAGS CFEDLAEEQA FDPYETLSQD ILAPEFNDHF SKLMARPAVA LHFQSIADGF KEAVRYVLPR LMLVPVYHCW HYFELLKQLK ACSEEQEDKE CLNQAITALM NLQGSMDRIY KQHSPRRRPG DPVCLFYNRQ LRSKHLAIKK MNEIQKNIDG WEGKDIGQCC NEFIMEGPLT RIGAKHERHI FLFDGLMISC KPNHGQTRLP GYSSAEYRLK EKFVMRKIQI CDKEDACEYR HAFELVSKDE NSVIFAAKSA EEKNNWMAAL ISLHYRSTLD RMLDSVLLKE ENEQPLRLPS PDMYRFVVTD SEENIVFEDN LQSRSGIPII KGGTVVKLIE RLTYHMYADP NFVRTFLTTY RSFCKPQELL NLLIERFEIP EPEPTEADKL ALEKGEQPIS ADLKRFRKEY VQPVQLRVLN VFRHWVEHHY YDFERDLELL ERLESFISSV RGKAMKKWVE SIAKIIKRKK QAQANGISHN ITFESSPPPV EWHISRTGQF ETFDLMTLHP IEIARQLTLL ESDLYRKVQP SELVGSVWTK EDKEINSPNL LKMIRHTTNL TLWFEKCIVE AENFEERVAV LSRIVEILQV FQDLNNFNGV LEIVSAVNSV SVYRLDHTFE ALQERKRRIL DDAVELSQDH FKKYLVKLKS INPPCVPFFG IYLTNILKTE EGNSDFLKRK GKDLINFSKR RKVAEITGEI QQYQNQPYCL RTEPEMRRFF ENLNPMGILS EKEFTDYLFN KSLEIEPRNC KQPPRFPRKS TFSLKSPGIR PNAGRHGSTS GTLRGHPTPL EREPYKISFS RIAETELEST VSAPTSPNTP STPPVSASSD HSVFLDVDLN SSCGSNTIFA PVLLPHSKTF FSSCGSLHKL SEEPLIPPPL PPRKKFDHDA LNSKGAVKSD DDPPAIPPRQ PPPPKVKPRV PVLMGTFDGP VPSPPPPPPR DPLPDTPPPV PLRPPEHFIN CPFNLQPPPL GHPHRDPDWL RDVSTCPNSP STPPTTPSPR IPRSCHLLSS SHSSLAHLPA PPVPPRQNSS PLLPKLPPKT YKRELSHPPL YRLPLLENAE TPQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SOS2 (Son of Sevenless Homolog 2 (SOS2))

Alternative Name: Sos2

Background: Son of sevenless homolog 2 (SOS-2) (mSOS-2),FUNCTION: Promotes the exchange of Ras-bound GDP by GTP. {ECO:0000250|UniProtKB:Q62245}.

Molecular Weight: 153.1 kDa

UniProt: Q02384

AlphaFold: Q02384

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, Hepatitis C, BCR Signaling