PTCHD1 Protein (AA 1-888) (His tag)

Catalog No. ABIN7563637

This Recombinant PTCHD1 protein is produced in HEK-293 Cells.

Quick Overview for PTCHD1 Protein (AA 1-888) (His tag) (ABIN7563637)

Target: PTCHD1 (Patched Domain Containing 1 (PTCHD1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-888

Purification tag / Conjugate: This PTCHD1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant ptchd1 Protein expressed in mammalian cells.

Sequence: MLRQVLHRGL RTCFSRLGHF IASHPVFFAS APVLISILLG ASFSRYQVEE SVEHLLAPQH SLAKIERNLV NSLFPVNRSK HRLYSDLQTP GRYGRVIVTS YQKANMLDQH HTDLILKLHT AVTKIQVPRP GFNYTFAHIC VLNNDKTCIV DDIVHVLEEL KNARATNRTN FAITYPITHL KDGRAVYNGH QLGGVTVHSK DRVKSAEAIQ LTYYLQSINS LNDMVAERWE SSFCDTVKLF QKSNSKVKIY PYTSSSLRED FQKTSRVSER YLVTSLILVV TMAILCCSMQ DCVRSKPWLG LLGLVTISLA TLTAAGIINL TGGKYNSTFL GVPFVMLGHG LYGTFEMLSS WRKTREDQHV KERTAEVYAD SMLSFSLTTA MYLVTFGIGA SPFTNIEAAR IFCCNSCIAI LFNYLYVLSF YGSSLVFTGY IENNYQHSIF CRKVPKPDVL QEKPAWYRFL LTARFSEETA EGEEANTYES HLLVCFLKRY YCDWITNTYV KPFVVLFYLI YISFALMGYL QVSEGSDLSN IVATATQTIE YTTAHQKYFN NYSPVIGFYI YESIEYWNSS VQEDVLEYTK GFVRISWFES YLNYLRKLNV STDLPKKNFT DMLRNSFLKT PQFSHFQEDI IFSKKYNDEV DVVASRMFLV AKTMETNREE LYDLLETLRR LSVTSKVKFI VFNPSFVYMD RYASSLGAPL HNSCISALFL LFFSAFLVAD SLINVWITLT VVSVEFGVIG FMTLWKVELD CISVLCLIYG INYTIDNCAP LLSTFVLGKD FTRTKWVKNA LEVHGVAILQ SYLCYIVGLF PLAAVPSNLT CTLFRCLFLI AFVTFFHCFA ILPVILTFLP PSKKKRKEKK NPENREEIEC VEMVDIDSTR VVDQITTV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: PTCHD1 (Patched Domain Containing 1 (PTCHD1))

Alternative Name: ptchd1

Background: Patched domain-containing protein 1,FUNCTION: Required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention. {ECO:0000269|PubMed:27007844}.

Molecular Weight: 101.5 kDa

UniProt: Q14B62

AlphaFold: Q14B62