TEX10 Protein (AA 1-928) (His tag)

Catalog No. ABIN7563746

This Recombinant TEX10 protein is expressed in HEK-293 Cells.

Quick Overview for TEX10 Protein (AA 1-928) (His tag) (ABIN7563746)

Target: TEX10 (Testis Expressed 10 (TEX10))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-928

Purification tag / Conjugate: This TEX10 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Tex10 Protein expressed in mammalian cells.

Sequence: MTKKRKRQDD FQKVKLKVGK KKPKLENATA TNFKTKAIHL PEQLKEDRTL PTNNRKLNIK DLLSQMHHYS GGVKQSALLG LKDLLSQYPF IIDAHLSNIL SEVTAVFTDR DANVRLAAVQ LLQFLAPKIR TEHISPFFPL VSAHLSSAMT HITEGIQEDS LKVLDILLEH YPALITGRSS ILLKNFVELI SHQQLSKGLV NRDRSQSWIL SVNPNRRVTS QQWRLKVLAR LSKFLQALAD GSSRLRESEG LQEQKETPHA TSNSIFINWK DHANDQQQIQ VYENGGSQPN VSSQFRLRCL GTLGTVDEDL SSPENLKGFI EIIIPLLIEC WIEALPPQLA ASVGSGVERE PLQVMQQVLN VISLLWKLSK QQDETHTLES WLRKNYLTDF KHHFMSHFPY ALKEITKQRK KDTNKSIKHC TVLSNNVDHL LLNLTLSDIM VSLANASTLQ NDSSWIETIR KFVTETLKGG TRLNSKQLNR LLGVSWRLIQ MQPNRDATEN LIKAVYTLYQ QRGLLLPVRT LLIKFFSKIY QKEELRSYRL RYRSKVLSRW LAGLPLQLSY LGSRNPELST QLIDIIHTAA SQANKDLLKN LQAAALRIYD PQEGAVVVLP AESQQRLVQL LYFLPTLPAD LLSQLSRCCI MGRLGSSLAV TLIGILYMRS SFSGWSHSVN DCLMTDVDYL SFLFSTLTGF SKEELTWLQN LRGVPHVVQT SLSPVLLYLT DLDQFLHHWD ITEAVCHSLL VIPARSQSFD IMQSAISKHL VGLTVIPDST AGCIFGVMCK LLDHTCVVNE ALLPFLASCC YSLLYFLLTL EKGDAEHLKK RDKLWEVCVS ILALLPRVLR LMLQSLRVNR ASPEELPVVG QLLRLLLQHV PLRSHMLTNA ILVQQIIKNI TTLKSGSVQE QWLTDLHYCF SVYISGHPQG PSILNALY Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TEX10 (Testis Expressed 10 (TEX10))

Alternative Name: Tex10

Background: Testis-expressed protein 10,FUNCTION: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). {ECO:0000250|UniProtKB:Q9NXF1, ECO:0000269|PubMed:22872859}.

Molecular Weight: 105.2 kDa

UniProt: Q3URQ0

AlphaFold: Q3URQ0