Chromosome 6 Open Reading Frame 170 (C6ORF170) (AA 1-1296) protein (His tag)

Catalog No. ABIN7563748

This Recombinant Chromosome 6 Open Reading Frame 170 protein is produced in HEK-293 Cells.

Quick Overview for Chromosome 6 Open Reading Frame 170 (C6ORF170) (AA 1-1296) protein (His tag) (ABIN7563748)

Target: Chromosome 6 Open Reading Frame 170 (C6ORF170)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1296

Purification tag / Conjugate: His tag

Purpose: Predefined custom protein recombinant Tbc1d32 Protein expressed in mammalian cells.

Sequence: MAHFSSEDEV MLQAMLRQLF QSVKEKITGA PSLECAEEIL LRLEETDENF HNYEFVKYLR QHICNMLGSM IEEEMEKCTS DQNQGEDSGY DTVVQHVTKR TQESKEYKEM MHSLKNIMMV VVEAMINKFE EDETRSEDRQ RKMQSGSCCT DNCSDSDSSF NQSYKFCQGK LRLILDQLDP GQPKEVRYEA LQTLCSAPPS DVLSCENWTT LCEKLTTSLS DPDPMFTDRI LKFYAQTFTL SPLHMTKEIY TSLAKYLEVY FLSRENHLPT LSTGVDITSP NVTRLLKKVR LLNEYQKEAP SFWIRHPEKY MEEIVESTLS LLSVKHEQSH LVPQKILDPI YFFALVDTKA VWFKKWMHAY YSRTAVLRLL EKKYKCLITT AVQQCVQYLE LCEAMKADEI LRHPKHCGTK QKSFYYSGQE LQYIYFIHSL CLLGRLLIYT QGRKLFPIKL KNRKDSVSLT NLLVLFTQLI YYSPSCPKMT SIMCSENYSP ASMVTDVLRM LCDQKECAVE CLYNSTVTEA LLLPIHNLTK GTAAAPDCSE TALIHIADIL ARIASVEEGL ILLLYGENMN SSEEESLTGA HIIAKFSKKL LEEDISIFSG SEMLPVVKGA FISVCRQIYG TCEGLQVLLP YGLHESIAKA WKKTSLLSER IPTPVEGSDS VSSVSQVSPN SVAWEDNLLD DLLNFAATPK GLLLLQRTGA INECVTFMLS QYAKKPQVNR QKKFGYEVLV VQVASTAAGA VALQNSGFIS ALITELWSNL ECGRDDVRLT HPRATPVDPI DRSCQKSFLA LVNLLSYPAV YELTANQELP NKAEYSLREV PTCIIDIMDR LIVLNSEAKI RSLLNYEQSH TFGLRLLSVV CCDLDALLLL EAQYQVSNML LHAQEENTFE ISENHRNFII DGLSVERNHV LVRINLIGGP SERILPPRML EKGDDPYPWP MFSSYPLPHC YQSEGPRSAD LKQDNDIGNL LSCFKMSDKQ TEWIENCRRQ FCKTMKSKPD AVHGSALGEL LEKFVLLLTE NPSECYFPSV EYTATDANVK NESLSSVQQL GMKMTVRYGR FLNLLKDGAE NELALVLKHC EKFLKQQQSP VTSSLLCLQG NYAGHDWFVS SLFMIMLGDK GKTFHFLQHF SRLLTSAFLW VPRLHNSRYL PVDTLGTGIH PIYFCSAHYI EMLLKAEVPL VFSAFHMSGF APSQICLQWI TQCFWNYLDW IEICHYIATC VVLGPDYQVY VCIAVLKHLQ RDILQHTQTQ DLQVFLKEEA LHGFRVSNYF EYMENLEQNY RPVLLRDMRS IRVQNT Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Chromosome 6 Open Reading Frame 170 (C6ORF170)

Alternative Name: Tbc1d32

Background: Protein broad-minded (TBC1 domain family member 32),FUNCTION: Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling. {ECO:0000269|PubMed:20159594}.

Molecular Weight: 148.1 kDa

UniProt: Q3URV1

AlphaFold: Q3URV1