Cyclin B3 Protein (CCNB3) (AA 1-1396) (His tag)

Catalog No. ABIN7564312

Product Details

Target: Cyclin B3 (CCNB3)

Protein Type: Recombinant

Protein Characteristics: AA 1-1396

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This Cyclin B3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Ccnb3 Protein expressed in mammalian cells.

Sequence: MPPPLLPKRS KLETEKAQSN KITPREEQQS EKIGKSNHAA SSSSSSTQGA VKRRSVFEDV TNASHSQCVQ SKEDNIELKS HVSKRTKKGV GEVTQKKIKS SKMGHVTSLS NMEKEFILDI PNKPKTLTTE EPSVFQKTLV LNEEPATKET CLMRKTLKSC AFHQETLLME KPLTLLVETE DYNEFDTELM TSKKKDKPED PTIIEEMTDL KKSVIRKVTL TSSPLWLKNK HVVQEEKPVI QEKSSFKRIS LVSNVVTTKE KPPVKKPHFR KKKPTTEMKS LLQEPSLEEK YNTQEDASIL KKPQVLQENT NNKDATLTEP VTFKGKHSAN EATHTKKPSS SKNNPDPQGK GTNLRPLRVH PVTYENEPMS SKKSTTKKKD SHFHGPSVLP DKHSPQMEVS TVKKSLALPN PTTEEKMLHF PVATVLEKQH NMGEAPCLKK PSPLRKQQQL PKRRRFFSNS AVQETVIRKP LFFKMSTTEK DPPSQWPSAL PKKHISPGEL SKQKKQHVSP KHNMEEDSQC WLDSAFKKQL SREEPASTHT PLKLEMQQAI TKETGFHLRN PLVLPTVTSE AKSLTKEPPS FREQNTSLLK RKSTTHTITL QQAQSEWQEM TDEDRNLFSI KPGSHRKEPI PEFLQNPLPP NENCLISQKL SHSMPFASQK TTSQERAHRK ESVASNDDKN FFSQDLFSPF SSADEDTLKF HKSLDFQEQV DRKNDSHKKM FDSQDSVSEE ESFLRKLFCK DRCSSTEELS QERTVALEQE FLLIKILNEN TSSDVDEPLS HQSPHIQNHS DTTKEALEAS EALEAPEALE TLEALVASED LEEPLNILEE LSTENMVALM KMLVTEDEST KDSFSGNYTA AREAHAEKSL SLEETSINEA ATLKESLSSQ EKHRAELVTV LKELLVLMKN PSLKRVALAF QENPSNNVET LLREVLALVE NSTADESTLQ EKPSTKTDVT PKELLALEEN SSNKKANPMD SLSFDHKPDT EMGEIARMVL TDEEYNIDTL YERVLALSQG LIAADQLSFT DLQNFEETKI VDEEEFFKSF LVFENKNSPN MSSNAFESRT DNSSAIMPSS KAFNPVENSN PYVSSSKSFK STLGAKETEI TIQDDSDSLE RIEKEGQDPL LNTIYAKDVF NYLKEREEKF LVQKYMDGQM ELTSDMRAIL VDWLVEIQGS FQMTHETLYL AVKIMDLYLM KAQCKKNHLQ LLGSTTYMIA AKFEESYPPS LSEFLFICED MYEKSDMVSL ESSILQTLNF DINIPTAYNF LRRYASCIHA SMKTLTLSRF ICEMTLQEYE YIEERPSKLA AASFILALYM RNLSNCVPTL EYFTGYKMAE LHILVRKLNH LLNFRSHSIL KNVFEKYSEE TYFEVAKIPP LSKQDLENLL NCALFH Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Cyclin B3 (CCNB3)

Alternative Name: Ccnb3 (CCNB3 Products)

Background: G2/mitotic-specific cyclin-B3,FUNCTION: Cyclins are positive regulatory subunits of the cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity). {ECO:0000250}.

Molecular Weight: 159.0 kDa

UniProt: Q810T2

AlphaFold: Q810T2

Pathways: Cell Division Cycle, Chromatin Binding