BCLAF1 Protein (AA 1-919) (His tag)

Catalog No. ABIN7564611

Recombinant BCLAF1 protein expressed in HEK-293 Cells.

Quick Overview for BCLAF1 Protein (AA 1-919) (His tag) (ABIN7564611)

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-919

Purification tag / Conjugate: This BCLAF1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Bclaf1 Protein expressed in mammalian cells.

Sequence: MGRSNSRSHS SRSKSRSQSS SRSRSRSHSR KKRYSSRSRS RTYSRSRSRD RIYSRDYRRD YRNNRGMRRP YGYRGRGRGY YQGGGGRYHR GGYRPVWNRR HSRSPRRGRS RSRSPKRRSV SSQRSRSRSR RSYRSSRSPR SSSSRSSSPY SKSPVSKRRG SQEKQTKKAE GEPQEESPLK SKSQEEPKDT FEHDPSESID EFNKSATSGD IWPGLSAYDN SPRSPHSPSP IATPPSQSSS CSDAPMLSTV HSAKNTPSQH SHSIQHSPER SGSGSVGNGS SRYSPSQNSP IHHIPSRRSP AKTITPQNAP REESRGRSSF YPEGDQETAK TGKFLKRFTD EESRVFLLDR GNIRDKEAPK EKGSEKGRAD GDWDDQEVLD YFSDKESAKQ KFHDSEGDDT EETEDYRQFR KSVLADQGKS FATSSHRNTE EEGPKYKSKV SLKGNRESDG FREEKNYKLK ETAYIVERPS TAKDKHKEED KGSDRITVKK EVQSPEQVKS EKLKELFDYS PPLHKSLDAR EKSIFREESP LRIKMIASDS HRPEVKLKMA PVPLDDSNRP ASLTKDRLLA STLVHSVKKE QEFRSIFDHI KLPQANKSTS ESFIQHIVSL VHHVKEQYFK SPAVTLNERF TSYQKATEEH STRQKSPEIH RRIDISPSAL RKHTRLAGEE RGFKEEIQKG DKKLRCDSAD LRHDIDRRRK ERSKERGDSK GSRESSGSRK QEKTPKDYKE YKPYKDDSKH KGRERDHSRS SSSSASPSSP SSREEKESKK EREEEFKTHH EMKDYSGFAG VSRPRGTFFR IRGRGRARGV FAGTNTGPNN SNTTFQKRPK EEEWDPEYTP KSKKYFLHDD RDDGVDYWAK RGRGRGTFQR GRGRFNFKKS GSSPKWTHDK YQGDGIVEDD EETMENNEEK KDRRKEEKE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: Bclaf1

Background: Bcl-2-associated transcription factor 1 (Btf),FUNCTION: Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA (By similarity). {ECO:0000250}.

Molecular Weight: 106.0 kDa

UniProt: Q8K019

AlphaFold: Q8K019

Pathways: Positive Regulation of Response to DNA Damage Stimulus