TDRD3 Protein (AA 1-743) (His tag)

Catalog No. ABIN7564790

This Recombinant TDRD3 protein is expressed in HEK-293 Cells.

Quick Overview for TDRD3 Protein (AA 1-743) (His tag) (ABIN7564790)

Target: TDRD3 (Tudor Domain Containing 3 (TDRD3))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-743

Purification tag / Conjugate: This TDRD3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Tdrd3 Protein expressed in mammalian cells.

Sequence: MAEVSGAALS QAGWYLSDEG VEACTSSPGK GSINDIILIA LNTDLRTIGK KFLPSDINGG KVEKLEGPCV LQIQKVRNVA APKDNEESQA APRMLRVQMT DGHTSCTAVE FSYISKISLN TPPGTKVKLS GTVDIKNGFL LLSDSNTTVL GGEVEHLIDK WALQRSLLKH NRSNIGAEGG PPPFLPFGQK CASNVQVDSR ELDRRKTLQV SLPAKPANDN DEFEKQRTAA IAEVAKSKET KTFGGGGGGA RSNLNIGAAG HRNREVLQKE KASKSESKNE GVYRELVDEK ALKHITEMGF SKEASRQALM DNANNLEAAL NVLLNSSKQK PAVGPPARGR GKGRGRGRSE DEEDLGTARP SAPSTLFDFL ESKMGTLNVE EPKSQPQHLH QGQHRGWNAE QNGMKDGTQS RHLPRNDTRQ PRNERPPRFQ KDTPTSKSTV ENSVLSRNRG SERPSSSSGS DVWAEERIKC DRPYSRYDRT KDASHPLGLQ HNDGAFKKRE NSMQNRPGRG PLYAEAKENP LPPEFVDYNN QRRGRRENQT GHPDHCYERK PRTMNSEAVS GLKIEKHFSV NTDYPRPVQS NSLGVPNGET APPLKGRRVG PIKSAGPVTA VPYDDKIFYN SGPKRRSGPI KPEKVIESSI PVEYAKVWKP GDECFALYWE DNKFYRAEVE ALHSSGMTAV VKFTDYGNYE EVLLSNIKPV QTEAWEEEGT YDHTIEFRRG GDGQPRRSTR PTQQFYQPPR ARN Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TDRD3 (Tudor Domain Containing 3 (TDRD3))

Alternative Name: Tdrd3

Background: Tudor domain-containing protein 3,FUNCTION: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. {ECO:0000250|UniProtKB:Q9H7E2}.

Molecular Weight: 82.3 kDa

UniProt: Q91W18

AlphaFold: Q91W18