ELP2 Protein (AA 1-831) (His tag)

Catalog No. ABIN7564800

Recombinant ELP2 protein expressed in HEK-293 Cells.

Quick Overview for ELP2 Protein (AA 1-831) (His tag) (ABIN7564800)

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-831

Purification tag / Conjugate: This ELP2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Elp2 Protein expressed in mammalian cells.

Sequence: MVSSVLEVSH VFCCPNRVRG ALSWNTGPGG LLAFGTSCSV VLYDPQKKVV ITNLNGHTAR VNCLQWIRTE DGSPSNELVS GGSDNRVIHW ELENNQVLKS VRLQGHEGPV CAVHAIYQSG PSEGEQHALI ASAASDSTVR IWSKKGSEVK YLQTLSFRDG FVLSVCLAIL PGTNVPVLAC GDDDCRIHLY IQQDDQFQKA LSLCGHEDWI RGVEWATFGR DLFLASCSQD CLIRIWRLYM KPASFETKDG SLRLKENTFT IKDGGVRTTV AVTLETVLAG HENWVNAVHW QPSFYKDGVL QQPVRLLSAS MDKTMILWAP DEESGVWLEQ VRVGEVGGNT LGFYDCQFGE NGTMIIAHAF HGALHLWKQS TVNPRQWAPE IVISGHFDGV QDLMWDPEGE FIITTSTDQT TRLFAPWKKK DQKDRSQVTW HEIARPQIHG YNIKCLAMID RFQFVSGADE KVLRVFSAPR NFVENFSVIS RQSLSHMLCD DQDLPEGATV PALGLSNKAL FQGDIASQPF EEDELISPAF GSPQVTFQPA VLNEPPTEDH LLQNTLWPEI QKLYGHGYEI VCVACNNSKT LLASACKASQ KEHAAIILWS TASWKQVQSL AFHTLTVTQM TFSPDDKFLL AVSRDRTWSL WKRQDATSSE FDPFFSLFAF TNKITSVHSR IIWSCDWSPD NKYFFTGSRD KKVVVWGECK SSHNPMEHPI RPCSSILDVG SSVTAVSVCP VLNPAQRYIV AIGLESGKIC IYSWNKTNQE INDWTSCVET NPSQSHSLGI RRLCWKSCSD DDDDDDDDDT EQSEEGPEWL HFASCGEDHT VKIYRVNRRA L Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Alternative Name: Elp2

Background: Elongator complex protein 2 (ELP2) (STAT3-interacting protein 1) (StIP1),FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator comple catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. {ECO:0000250|UniProtKB:Q6IA86}.

Molecular Weight: 93.1 kDa

UniProt: Q91WG4

AlphaFold: Q91WG4

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus