FAM115C Protein (AA 1-919) (His tag)

Catalog No. ABIN7564847

This Recombinant FAM115C protein is expressed in HEK-293 Cells.

Quick Overview for FAM115C Protein (AA 1-919) (His tag) (ABIN7564847)

Target: FAM115C (Family with Sequence Similarity 115, Member C (FAM115C))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-919

Purification tag / Conjugate: This FAM115C protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Tcaf2 Protein expressed in mammalian cells.

Sequence: MATTPDAAFE ALMNGVTSWD LPKEFTPSEL LLIGEAAFPV MVNDKGQVLI AVSFYGQGRL VVVSHESYLM HAGLAPFLLN AVSWLCPSPG TPIEVHSSLA SLVNILRGSG INALVQPEPG EALGVYCIDA YNDTLTKKLV QFVKRGGGLL IGGQAWNWAS QHGSDKVLFS FPGNKVTSVA GVYFTDVYGD INRFKVSKKI PKIPLYIRCW EELRHDQDQL LDGISMLDVR TGGVPSQLLV HGSLAFPLGL DNSFLSCFLA AAHYGRGRVV LAAHEAMLCA PKMEPFLLNA IRWLSRGQED NIGVNTRLKN LNSLLLKHGL KCSLESHLTD DMCVYCCAAY SDQEAKKIQE FVAEGGGLLI GGQSWWWASQ NPGSSALGSF PGNVILNTFG LSILPRTVSP GCFPILHIDI RNYHFRGALS EFQAMLNHKE GNLEKRYSGK LGVDGAGFLQ IPAQGVPAYL SVHRILRKIL RQAGLPAVSK SNPVSSHSYE AAILQLATEL AHSGSDCSQI AHNLSSQTCS SNLSSSEHPI TVEINGTNPG DRDVWMSTGL YLLEGQSTEI SVSEPAASAG LKVQIGCHTD DLTFAIKLFR APVVTYQCCM NRTQRSVSCL WGGLLYIIVP KGCQLGPVSV TITNAVPAPY YKLGKTSLEE WKSCIQKNLG PWGELATDNV ILTVPTASLK TLENPEPLLQ LWDEMMQAVA RLASQPFPFQ RPERIVADVQ LSAGWMHSGY PIMCHMESVQ ELVSLANIRS KGLWGPIHEL GHNQQCRGWE FPPHTTEATC NLWSVYVHET VLGIPRAQAH PQLKPEEREK RIKEHLQKGA PLQNWNVWTA LETYLQLQEV FGWEPFITLF AEYQTIFYIP EDNECKMNIW LKLFSEKVQK NLVPFFEAWG WPIQKDVAED LACYPSWEDH PLRMYMGSE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: FAM115C (Family with Sequence Similarity 115, Member C (FAM115C))

Alternative Name: Tcaf2

Background: TRPM8 channel-associated factor 2 (TRP channel-associated factor 2),FUNCTION: Negatively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration stimulation in a TRPM8-dependent manner. {ECO:0000250|UniProtKB:A6NFQ2}.

Molecular Weight: 101.6 kDa

UniProt: Q921K8

AlphaFold: Q921K8