FANCA Protein (AA 1-1439) (His tag)

Catalog No. ABIN7565113

This Recombinant FANCA protein is produced in HEK-293 Cells.

Quick Overview for FANCA Protein (AA 1-1439) (His tag) (ABIN7565113)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1439

Purification tag / Conjugate: This FANCA protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Fanca Protein expressed in mammalian cells.

Sequence: MPGSPARGAA MGGGPRGLRK TWTELLAGRV KKQKYDPERE QKLKDSALKL LRYHQNMHDL LLEVEEPQCK RLRLSELIDR DSADASSDRS ASFIRSAFRD QASRLGVPVG VLSAKVFARS VQQVCVEPSH PVLLSPEQSK KLSSLLMIAR HLLAQNMFSR LTFCQELWKA QNSLLLEAMW RLHTHSVVSL QELLQSHPDS EAMAMWLFRN LRSLCEQIGA SCPSPDTTEA MLSGLVQLLI SRGFQGSSDP RRLVEPERLP QVATDVLQRM LAFSLDTLEA DPQTTLDCQA VSGWIPIYSG HTCCGVVTEN SLKSFFSHTL TQILTHKPVL KVSDAIQMQK EWSFAKTHHL LTDLHCRVLA TLGPEESVGR LQEVLEMQEV NWQHVLSCVS TLVVCFPEAQ QLVKGWVASL MARAFESYHL DSMVTAFLIV RQATLEGPYV FPSYADWFKE SFGSSHGYHS CSKKTLVFLF KFLSDLVPWE APRYMQVHIF HPPLVPSKYH SLLTDYISLA KTRLADLKVS LENVGLYEDL SSPGDIAERE SQAVQDVKKA IMVFEQTGKI PMPVLEASIF RRPYYVSHFL PTLLAPRVLP EVPDPRVALI ETLKRADKIP SSIYDAYRKA CASAEKQQPE NATSAQRTEA DCAKEPLGLL TAALEELRAL MTDPTQYSVI SAQVAVVSEK LNAVLGHRND GGSLQRAKIQ LSVLPSTLQK QDQAVVDLLL TAFCQNLMAA SSFVPPERQS PWAVLFVRTL CGHVLLPAVL TRLRQLLRHQ GQSLSTSHVL GLAALAVHLG ECRSMLPEVD PDVLAPSAGS LCVPDFLNSL LTCRTRDSLL FCMNFCTAAV SYCLCKFSAL RNCLSPGLIK KFQFVVLRLF PEARAPCAPE HAACVPWRPL YLPSADWQRA ALSLWRRDSF QELLKDKEFY LTYRDWVQLE LEIQPEADVL SDMERHDFHQ WAIYERYLPA PTALGGCGGD LEEACTVLVS EIMDFHQSSR SYNHSEDSDL VLGGRTGNKD ILSRLQEIAL DLELDQGSAV PHGCSTPQSH FLFRVFRRRL QALARPDSMA TSLRRQQELL TCKRLLLCLP PSVLVGGPQA GQPISPNCGE FFSLVNSELR NFCCHGSVLT SDITIHFFRG LLRVCLRSQD PALVANQTLT ECQTKCPVIL TSALLWWSSL EPVLCGRWMR CYQSPLPREL RRLQEAREFA SNFASASASP APSPAWIAAA ALHFAWRGVR KEDVTAHLQR LDCQREELLI ALFFFSLMGL LSSYLTQRDT AEHLKAVDIC AEVLTCLERR KVSWLVLFQL TEKDAKLGHL LHLAPDQHTR LLPLAFYSLL SCFSEGAAVR EAAFLHVAVD MYLKLLQLFV DGETRLQGHS ESQGSPVQLI TKARVFLLQL IPQCPKQCFS NMTELLAGRG DCDPEVSNAL RQRQQADPSF DLYQEPQLF Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Alternative Name: Fanca

Background: Fanconi anemia group A protein homolog (Protein FACA),FUNCTION: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability (By similarity). {ECO:0000250}.

Molecular Weight: 161.2 kDa

UniProt: Q9JL70

AlphaFold: Q9JL70

Pathways: DNA Damage Repair