CD38 Protein (Fc Tag)
Quick Overview for CD38 Protein (Fc Tag) (ABIN7566110)
Target
See all CD38 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD38 protein is labelled with Fc Tag.
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Purpose
- CD38 (human):Fc (human) (rec.)
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Cross-Reactivity
- Human
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Characteristics
- The extracellular domain of human CD38 (aa 43 - 300) is fused to the N-terminus of the Fc region of human IgG1.
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Sterility
- Sterile filtered
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Endotoxin Level
- <5EU/mg protein (LAL test, Lonza).
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CD38 (AA 43-300) protein (His tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 43-300) protein (Fc Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 43-300) protein (His-Avi Tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 1-304) protein (His tag)custom-made Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD38 (AA 1-300) protein (His tag)custom-made Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD38 (AA 45-304) protein (His tag)Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 44-301) protein (His tag)Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 43-300) protein (Fc-His Tag)Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD38 (AA 43-300) (Active) protein (His tag)Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD38 (AA 43-300) (Active) protein (Fc Tag,FITC)Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
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Handling Advice
- Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- CD38
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Background
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ADP-ribosyl Cyclase 1, Cyclic ADP-ribose Hydrolase 1, ADPRC 1, T10
CD38, also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.
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Molecular Weight
- ~70kDa (SDS-PAGE)
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UniProt
- P28907
Target
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