CD38 Protein (AA 43-300) (His tag)
(1 reference)-
- Target See all CD38 Proteins
- CD38
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 43-300
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD38 protein is labelled with His tag.
- Sequence
- AA 43-300
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.7 kDa. The protein migrates as 30-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD38 Protein
-
CD38 (AA 43-300) protein (His tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 43-300) protein (Fc Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 43-300) protein (His-Avi Tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 45-304) protein (His tag)Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 44-301) protein (His tag)Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD38 (AA 43-300) (Active) protein (Fc Tag,FITC)Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD38 protein (Fc Tag)Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
CD38 (AA 45-300) protein (His tag)Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
CD38 (AA 1-300) protein (GST tag)Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
CD38 (AA 201-300) protein (GST tag)Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- 50 mM MES, 100 mM NaCl, pH 6.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
-
-
: "ImmunoPET imaging of multiple myeloma with [68Ga]Ga-NOTA-Nb1053." in: European journal of nuclear medicine and molecular imaging, Vol. 48, Issue 9, pp. 2749-2760, (2021) (PubMed).
-
: "ImmunoPET imaging of multiple myeloma with [68Ga]Ga-NOTA-Nb1053." in: European journal of nuclear medicine and molecular imaging, Vol. 48, Issue 9, pp. 2749-2760, (2021) (PubMed).
-
- Target
- CD38
- Abstract
- CD38 Products
- Synonyms
- T10 Protein, Cd38-rs1 Protein, cd38 Protein, ADPRC 1 Protein, cADPr hydrolase 1 Protein, CD38 molecule Protein, CD38 antigen Protein, CD38 molecule L homeolog Protein, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Protein, CD38 Protein, Cd38 Protein, cd38.L Protein
- Background
- CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
- Molecular Weight
- 30.7 kDa
- NCBI Accession
- NP_001766
-
