NR1H2 Protein (His tag)
(1 reference)Quick Overview for NR1H2 Protein (His tag) (ABIN7578533)
Target
See all NR1H2 ProteinsProtein Type
Origin
Source
Application
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Purification tag / Conjugate
- This NR1H2 protein is labelled with His tag.
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Purpose
- Recombinant Human NR1H2/LXRb, N-His
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Sequence
- Lys72-Glu460
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Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-446) protein (His tag)
custom-made NR1H2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-460) protein (His tag)custom-made NR1H2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-461) protein (GST tag)NR1H2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) protein (Myc-DYKDDDDK Tag)NR1H2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in sterile water for a stock solution.
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Buffer
- Lyophilized from a solution in PBS pH 7.4, 0.02 % NLS, 1 mM EDTA, 4 % Trehalose, 1 % Mannitol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
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: "Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction." in: Nature communications, Vol. 16, Issue 1, pp. 2112, (2025) (PubMed).
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: "Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction." in: Nature communications, Vol. 16, Issue 1, pp. 2112, (2025) (PubMed).
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- NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
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Alternative Name
- NR1H2/LXRb
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Background
- UNR, Oxysterols receptor LXR-beta, LXRB, NR1H2, Nuclear receptor subfamily 1 group H member 2, Liver X receptor beta, NER, Ubiquitously-expressed nuclear receptor, Nuclear receptor NER
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Molecular Weight
- 46.05 kDa
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UniProt
- P55055
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding
Target
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