ALDH1A1 Protein (AA 1-501)
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- Target See all ALDH1A1 Proteins
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 1-501
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS), Enzyme Activity Assay (EAA)
- Sequence
- MSSSGTPDLP VLLTDLKIQY TKIFINNEWH DSVSGKKFPV FNPATEEELC QVEEGDKEDV DKAVKAARQA FQIGSPWRTM DASERGRLLY KLADLIERDR LLLATMESMN GGKLYSNAYL NDLAGCIKTL RYCAGWADKI QGRTIPIDGN FFTYTRHEPI GVCGQIIPWN FPLVMLIWKI GPALSCGNTV VVKPAEQTPL TALHVASLIK EAGFPPGVVN IVPGYGPTAG AAISSHMDID KVAFTGSTEV GKLIKEAAGK SNLKRVTLEL GGKSPCIVLA DADLDNAVEF AHHGVFYHQG QCCIAASRIF VEESIYDEFV RRSVERAKKY ILGNPLTPGV TQGPQIDKEQ YDKILDLIES GKKEGAKLEC GGGPWGNKGY FVQPTVFSNV TDEMRIAKEE IFGPVQQIMK FKSLDDVIKR ANNTFYGLSA GVFTKDIDKA ITISSALQAG TVWVNCYGVV SAQCPFGGFK MSGNGRELGE YGFHEYTEVK TVTVKISQKN S
- Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is > 700pmol/min/ug, and is defined as the amount of enzyme that catalyze the oxidation of 1.0 pmole propioaldehyde by NAD per minute at pH 8.8 at 37°C.
- Top Product
- Discover our top product ALDH1A1 Protein
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Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) protein (GST tag)
ALDH1A1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) proteinALDH1A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) protein (Myc-DYKDDDDK Tag)ALDH1A1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 2-501) (Active) protein (His tag)ALDH1A1 Origin: Human Host: Escherichia coli (E. coli) > 95 % AcA, CC Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
- Alternative Name
- Aldehyde Dehydrogenase 1-A1/ ALDH1A1 (ALDH1A1 Products)
- Background
- Aldehyde dehydrogenase 1A1 (ALDH1A1), also known as retinal dehydrogenase 1, is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. (Retinal + NAD+ + H2O = retinoate + NADH) Recombinant ALDH1A1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 54.8 kDa (501aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_000680
- Pathways
- Dopaminergic Neurogenesis
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