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CD9 Protein (CD9) (AA 112-195) (hIgG-His-tag)

Recombinant CD9 protein expressed in Baculovirus infected Insect Cells.
Catalog No. ABIN7596342

Quick Overview for CD9 Protein (CD9) (AA 112-195) (hIgG-His-tag) (ABIN7596342)

Target

See all CD9 Proteins
CD9

Protein Type

Recombinant

Origin

  • 15
  • 1
Human

Source

  • 6
  • 5
  • 2
  • 2
Baculovirus infected Insect Cells

Application

SDS-PAGE (SDS)

Purity

> 95% by SDS - PAGE
  • Protein Characteristics

    AA 112-195

    Purification tag / Conjugate

    This CD9 protein is labelled with hIgG-His-tag.

    Sequence

    SHKDEVI KEVQEFYKDT YNKLKTKDEP QRETLKAIHY ALNCCGLAGG VEQFISDICP KKDVLETFTV KSCPDAIKEV FDNKFHI

    Endotoxin Level

    < 1 EU per 1ug of protein (determined by LAL method)
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target

    CD9

    Alternative Name

    CD9

    Background

    CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant human CD9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    Molecular Weight

    36.9kDa (326aa)

    NCBI Accession

    NP_001760

    Pathways

    Response to Water Deprivation, Cell-Cell Junction Organization
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