CLDN18.2 protein (DYKDDDDK Tag,Strep Tag)
Origin: Human
Host: HEK-293 Cells
Synthetic Nanodisc
cryo-EM, ELISA, Imm, PhD, SPR
-
- Target
- CLDN18.2
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- DYKDDDDK Tag,Strep Tag
- Application
- Cryogenic electron microscopy (cryo-EM), ELISA, Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human CLDN18.2-Strep full length protein-synthetic nanodisc
-
CLDN18.2 protein
Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
CLDN18.2 protein-VLPOrigin: Human Host: HEK-293 Cells VLP
-
- Comment
-
Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- CLDN18.2
- Background
-
SFTA5, SFTPJ
A member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. - Molecular Weight
- The human full length CLDN18.2-Strep Protein has a MW of 27.5 kDa
- UniProt
- P56856
-
You are here:
