MLC1 Protein (DYKDDDDK Tag,Strep Tag)

Catalog No. ABIN7596567

Synthetic Nanodisc MLC1 protein expressed in HEK-293 Cells.

Quick Overview for MLC1 Protein (DYKDDDDK Tag,Strep Tag) (ABIN7596567)

Target: MLC1

Protein Type: Synthetic Nanodisc

Origin: Human

Source: HEK-293 Cells

Application: Cryogenic electron microscopy (cryo-EM), ELISA, Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)

Product Details

Purification tag / Conjugate: This MLC1 protein is labelled with DYKDDDDK Tag,Strep Tag.

Purpose: Human MLC1-Strep full length protein-synthetic nanodisc

Application Details

Comment:

Advantages:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins
• Mammalian cell expression system ensures post- translational modifications

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: MLC1

Background: LVM, MLC, VL
The function of this protein is unknown, however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: The human full length MLC1-Strep protein has a MW of 41.2 kDa

UniProt: Q15049