MC4R Protein (DYKDDDDK Tag,Strep Tag)
-
- Target See all MC4R Proteins
- MC4R (Melanocortin 4 Receptor (MC4R))
- Protein Type
- Synthetic Nanodisc
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MC4R protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human MC4R-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product MC4R Protein
-
-
- Comment
-
Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- MC4R (Melanocortin 4 Receptor (MC4R))
- Alternative Name
- MC4R (MC4R Products)
- Background
-
BMIQ20
The protein is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. - Molecular Weight
- The human full length MC4R-Strep protein has a MW of 36.9 kDa
- UniProt
- P32245
- Pathways
- Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
-