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MC4R Protein (DYKDDDDK Tag,Strep Tag)

MC4R Origin: Human Host: HEK-293 Cells Synthetic Nanodisc ELISA, cryo-EM, Imm, PhD, SPR
Catalog No. ABIN7596601
  • Target See all MC4R Proteins
    MC4R (Melanocortin 4 Receptor (MC4R))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 8
    • 3
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MC4R protein is labelled with DYKDDDDK Tag,Strep Tag.
    Application
    ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
    Purpose
    Human MC4R-Strep full length protein-synthetic nanodisc
    Top Product
    Discover our top product MC4R Protein
  • Comment

    Advantages:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    • Mammalian cell expression system ensures post- translational modifications

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    MC4R (Melanocortin 4 Receptor (MC4R))
    Alternative Name
    MC4R (MC4R Products)
    Background
    BMIQ20
    The protein is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.
    Molecular Weight
    The human full length MC4R-Strep protein has a MW of 36.9 kDa
    UniProt
    P32245
    Pathways
    Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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