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Prostaglandin D2 Receptor 2 (PTGDR2) protein (DYKDDDDK Tag,Strep Tag)

This Synthetic Nanodisc protein is produced in HEK-293 Cells.
Catalog No. ABIN7596604

Quick Overview for Prostaglandin D2 Receptor 2 (PTGDR2) protein (DYKDDDDK Tag,Strep Tag) (ABIN7596604)

Target

Prostaglandin D2 Receptor 2 (PTGDR2)

Protein Type

Synthetic Nanodisc

Origin

  • 3
  • 2
Human

Source

  • 3
  • 2
HEK-293 Cells

Application

ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
  • Purification tag / Conjugate

    DYKDDDDK Tag,Strep Tag

    Purpose

    Human PTGDR2-Strep full length protein-synthetic nanodisc
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    Product
    Expression System
    Conjugate
    Origin
    Price starts at
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $16,231.82
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    Price starts at $20,480.57

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  • Comment

    Advantages:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    • Mammalian cell expression system ensures post- translational modifications

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    Prostaglandin D2 Receptor 2 (PTGDR2)

    Alternative Name

    PTGDR2

    Background

    CD294, CRTH2, DL1R, DP2, GPR44
    The protein is a G-protein-coupled receptor that is preferentially expressed in CD4 effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.

    Molecular Weight

    The human full length PTGDR2-Strep protein has a MW of 43.3 kDa

    UniProt

    Q9Y5Y4

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling
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