GIPR Protein (DYKDDDDK Tag,Strep Tag)
-
- Target See all GIPR Proteins
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Protein Type
- Synthetic Nanodisc
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GIPR protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human GIPR-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product GIPR Protein
-
Gastric Inhibitory Polypeptide Receptor (GIPR) protein
GIPR Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Gastric Inhibitory Polypeptide Receptor (GIPR) (AA 19-134) protein (Fc Tag)GIPR Origin: Mouse Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Gastric Inhibitory Polypeptide Receptor (GIPR) (AA 22-138) protein (Fc Tag)GIPR Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
-
- Comment
-
Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Alternative Name
- GIPR (GIPR Products)
- Background
-
PGQTL2
A G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. - Molecular Weight
- The human full length GIPR-Strep protein has a MW of 53.2 kDa
- UniProt
- P48546
- Pathways
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
-
