GIPR Protein
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- Target See all GIPR Proteins
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human GIPR full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GIPR Protein
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Gastric Inhibitory Polypeptide Receptor (GIPR) (AA 22-138) protein (His tag)
Crystallography grade GIPR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Gastric Inhibitory Polypeptide Receptor (GIPR) (AA 19-134) protein (His tag)Crystallography grade GIPR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Gastric Inhibitory Polypeptide Receptor (GIPR) (AA 22-466) protein (rho-1D4 tag)Crystallography grade GIPR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Gastric Inhibitory Polypeptide Receptor (GIPR) (AA 19-460) protein (rho-1D4 tag)Crystallography grade GIPR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Alternative Name
- GIPR (GIPR Products)
- Synonyms
- GIPR Protein, PGQTL2 Protein, GIP-R Protein, Gm1081 Protein, Gm160 Protein, Gippr Protein, RATGIPPR Protein, gastric inhibitory polypeptide receptor Protein, glucagon receptor Protein, GIPR Protein, LOC100303705 Protein, Gipr Protein
- Background
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PGQTL2
Description: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011] - Molecular Weight
- The human full length GIPR protein has a MW of 53 kDa
- UniProt
- P48546
- Pathways
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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