CHRM1 Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all CHRM1 Proteins
- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CHRM1 protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human ACM1-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product CHRM1 Protein
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!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $16,231.82Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $20,480.57Your project requires further customization? Contact us and discover our custom protein solutions
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Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 1-460) protein (His tag)
custom-made CHRM1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 1-460) protein (His tag)custom-made CHRM1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 210-366), (Cytoplasmic Domain), (Cytosolic) protein (His tag)CHRM1 Origin: Rat Host: Yeast Recombinant > 90 % SDS
Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 210-366), (Cytoplasmic Domain), (Cytosolic) protein (His tag)CHRM1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
- Alternative Name
- ACM1 (CHRM1 Products)
- Background
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HM1, M1, M1R
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length ACM1-Strep protein has a MW of 51.4 kDa
- UniProt
- P11229
- Pathways
- Synaptic Membrane
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