CRHR2 Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all CRHR2 Proteins
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CRHR2 protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human CRFR2-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product CRHR2 Protein
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Corticotropin Releasing Hormone Receptor 2 (CRHR2) (AA 1-411) protein (His tag)
custom-made CRHR2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Corticotropin Releasing Hormone Receptor 2 (CRHR2) (AA 1-411) protein (GST tag)CRHR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- Alternative Name
- CRFR2 (CRHR2 Products)
- Background
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CRF-RB, CRF2, CRFR2, HM-CRF
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011] - Molecular Weight
- The human full length CRFR2-Strep protein has a MW of 47.7 kDa
- UniProt
- Q13324
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour
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