Dopamine d2 Receptor Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all Dopamine d2 Receptor (DRD2) Proteins
- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Dopamine d2 Receptor protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human DRD2-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product DRD2 Protein
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Dopamine Receptor D2 (DRD2) (AA 1-443) protein (His tag)
custom-made DRD2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Dopamine Receptor D2 (DRD2) (AA 1-444) protein (His tag)custom-made DRD2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Dopamine Receptor D2 (DRD2) (AA 1-110) protein (GST tag)DRD2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
- Alternative Name
- DRD2 (DRD2 Products)
- Background
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D2DR, D2R
This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia, other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. - Molecular Weight
- The human full length DRD2-Strep protein has a MW of 50.6 kDa
- UniProt
- P14416
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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