Endothelin-1 Receptor Protein (DYKDDDDK Tag,Strep Tag)
EDNRA
Origin: Human
Host: HEK-293 Cells
Synthetic Nanodisc
Imm, ELISA, cryo-EM, PhD, SPR
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- Target See all Endothelin-1 Receptor (EDNRA) Proteins
- Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Endothelin-1 Receptor protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human EDNRA-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product EDNRA Protein
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
- Alternative Name
- EDNRA (EDNRA Products)
- Background
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ET-A, ETA, ETA-R, ETAR, ETRA, MFDA, hET-AR
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] - Molecular Weight
- The human full length EDNRA-Strep protein has a MW of 48.7 kDa
- UniProt
- P25101
- Pathways
- cAMP Metabolic Process
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