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Endothelin-1 Receptor Products

(Endothelin Receptor Type A (EDNRA))
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

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Featured Endothelin-1 Receptor Categories

Endothelin-1 Receptor Antibodies

High quality antibodies with extensive validation data.

Endothelin-1 Receptor ELISA Kits

Reliable ELISA kits for a wide range of species.

Endothelin-1 Receptor Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Endothelin-1 Receptor Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC, ICC
Validations
  • (4)
Cat. No. ABIN6257158
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (3)
Cat. No. ABIN390401
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN515162
Quantity 100 μg
Datasheet Datasheet

Recommended Endothelin-1 Receptor ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966515
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966514
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955573
Quantity 96 tests
Datasheet Datasheet

Recommended Endothelin-1 Receptor Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352330
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352329
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3097059
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Endothelin-1 Receptor products

Lampmann, Borger, Konczalla, Gispert, Auburger, Vatter, Güresir: "Experimental Induction of Intracranial Aneurysms in Rats: A New Model Utilizing a Genetic Modification within the EDNRA Gene." in: Brain sciences, Vol. 12, Issue 9, (2022) (PubMed).

Dufek, Meehan, Delimont, Cheung, Gratton, Phillips, Song, Liu, Cosgrove: "Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease." in: Kidney international, Vol. 90, Issue 2, pp. 300-310, (2017) (PubMed).

Meehan, Delimont, Dufek, Zallocchi, Phillips, Gratton, Cosgrove: "Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice." in: Hearing research, Vol. 341, pp. 100-108, (2016) (PubMed).

Kobayashi, Yoshimoto, Yamamoto, Kimura, Okuda: "Roles of EDNs in regulating oviductal NO synthesis and smooth muscle motility in cows." in: Reproduction (Cambridge, England), Vol. 151, Issue 6, pp. 615-22, (2016) (PubMed).

Shinoda, Shinya, Ito, Ishizuka-Katsura, Ohsawa, Terada, Hirata, Kawano, Yamamoto, Tomita, Ishibashi, Hirabayashi, Kimura-Someya, Shirouzu, Yokoyama: "Cell-free methods to produce structurally intact mammalian membrane proteins." in: Scientific reports, Vol. 6, pp. 30442, (2016) (PubMed).

Cook, Brais, Qian, Hak, Corrie: "Endothelin-1 and endothelin B receptor expression in pancreatic adenocarcinoma." in: Journal of clinical pathology, Vol. 68, Issue 4, pp. 309-13, (2015) (PubMed).

Gordon, Weaver, Zechi-Ceide, Madsen, Tavares, Oufadem, Kurihara, Adameyko, Picard, Breton, Pierrot, Biosse-Duplan, Voisin, Masson, Bole-Feysot, Nitschké, Delrue, Lacombe, Guion-Almeida, Moura, Garib et al.: "Mutations in the endothelin receptor type A cause mandibulofacial dysostosis with alopecia. ..." in: American journal of human genetics, Vol. 96, Issue 4, pp. 519-31, (2015) (PubMed).

Gärtner, Seidel, Schulz, Gummert, Milting: "Desensitization and internalization of endothelin receptor A: impact of G protein-coupled receptor kinase 2 (GRK2)-mediated phosphorylation." in: The Journal of biological chemistry, Vol. 288, Issue 45, pp. 32138-48, (2013) (PubMed).

Keator, Mah, Ohm, Slayden: "Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium." in: Human reproduction (Oxford, England), Vol. 26, Issue 7, pp. 1715-28, (2011) (PubMed).

Asundi, Reed, Arca, McCutcheon, Ferrando, Clark, Luis, Tien, Firestein, Polakis: "An antibody-drug conjugate targeting the endothelin B receptor for the treatment of melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 5, pp. 965-75, (2011) (PubMed).

Synonyms and alternative names related to Endothelin-1 Receptor

endothelin receptor type A (EDNRA), endothelin receptor type A (Ednra), endothelin receptor type Aa (ednraa), endothelin receptor type A L homeolog (ednra.L), endothelin receptor type A (ednra), endothelin receptor type Ab (ednrab), ednr-a, ednra, ednraa, Endor, ET-A, ET-AR, ETA, Eta, ETa, eta, ETA-R, ETAR, etar, ETRA, etra, Gpcr10, hET-AR, RGD1559432, wu:fb75g12, zgc:85942

Protein level used designations for Endothelin-1 Receptor

  • G protein-coupled receptor
  • endothelin receptor subtype A
  • endothelin-1 receptor
  • endothelin-1-specific receptor
  • endothelin A receptor
  • ET-A
  • G-protein coupled receptor 10
  • Ednra2
  • endothelin receptor A
  • endothelin receptor type A
  • endothelin type-A receptor 2
  • etID40953.1
  • ET-AR
  • Endothelin-1 receptor type A
  • endothelin receptor type A a
  • LOW QUALITY PROTEIN: endothelin-1 receptor
  • ednrA1
  • endothelin receptor type Ab
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