KCNE1 Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all KCNE1 Proteins
- KCNE1 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KCNE1 protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human KCNE1-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product KCNE1 Protein
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- KCNE1 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1))
- Alternative Name
- KCNE1 (KCNE1 Products)
- Background
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ISK, JLNS, JLNS2, LQT2/5, LQT5, MinK
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length KCNE1-Strep protein has a MW of 14.7 kDa
- UniProt
- P15382
- Pathways
- Sensory Perception of Sound
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