HTR3C Protein (DYKDDDDK Tag,Strep Tag)
HTR3C
Origin: Human
Host: HEK-293 Cells
Synthetic Nanodisc
cryo-EM, ELISA, Imm, PhD, SPR
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- Target See all HTR3C products
- HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HTR3C protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Cryogenic electron microscopy (cryo-EM), ELISA, Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human 5HT3C-Strep full length protein-synthetic nanodisc
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))
- Alternative Name
- 5HT3C (HTR3C Products)
- Background
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N/A
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length 5HT3C-Strep protein has a MW of 50.2 kDa
- UniProt
- Q8WXA8
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